🧠 Brain food updates: intermittent fasting and mental health, dietary patterns for Parkinson's disease, magnesium intake in depression and more

What's New in Nutrition and Brain Health

Today's research summary includes a systematic review on effects of intermittent fasting for cognitive and mental health, both a meta-analysis AND a systematic review exploring the role of dietary patterns in Parkinson's disease, a dose-response analysis of magnesium intake in relationship to depression, discussion around food addiction prevalence in individuals with bulimia nervosa and more. Inclusive of publication dates 05/01/24-05/15/24, Part 2 and 5/16-5/31/24.

Interested in an audio summary, highlighting some of the themes and papers of interest? It's available below. If you are directed to 'listen online’, just navigate to today's edition in archives at the bottom of the page.

Insights or suggestions? Hit reply to let me know.

Sarah Ferreira, MS, MPH, RD

Research Area

• Cognitive Function, Memory and Neurodegeneration

• Mood and Mental Health

• Eating Disorders

• Addiction, Eating Behavior and Food Choice

• Neurodevelopmental Outcomes

• Sleep Health and Insomnia

• Brain Injury

• Migraines, Epilepsy and Other Neurological

• Other

Cognitive Function, Memory and Neurodegeneration

• A Genome-Wide Interaction Study of Erythrocyte ω-3 Polyunsaturated Fatty Acid Species and Memory in the Framingham Heart Study Offspring Cohort

• A new intestinal supplement 'Synbiotics' therapeutically regulates gut microbiota and activates PPARs pathway to inhibit Alzheimer's disease progression in mouse models

• Association between adding salt in food and dementia in European descent: A mendelian randomization study

• Association between major dietary patterns and Parkinson's disease risk: a case-control study

• Association of dietary selenium intake and all-cause mortality of Parkinson's disease and its interaction with blood cadmium level: a retrospective cohort study

• Association of Egg Intake With Alzheimer's Dementia Risk in Older Adults: The Rush Memory and Aging Project

• Association of physical activity and vitamin D deficiency with cognitive impairment in older adults: a population based cross-sectional analysis

• Caffeoylquinic Acid Mitigates Neuronal Loss and Cognitive Decline in 5XFAD Mice Without Reducing the Amyloid-β Plaque Burden

• Chronic stress induces Alzheimer's disease-like pathologies through DNA damage-Chk1-CIP2A signaling ^{_{(Vitamin C discussed)}}

• Clinical predictors of Alzheimer's disease-like brain atrophy in individuals with memory complaints _{(considers assessment of vitamin deficiencies)}

• Co-administration of probiotics and vitamin D reduced disease severity and complications in patients with Parkinson's disease: a randomized controlled clinical trial

• Development of White Cabbage, Coffee, and Red Onion Extracts as Natural Phosphodiesterase-4B (PDE4B) Inhibitors for Cognitive Dysfunction: In Vitro and In Silico Studies

• Dietary (Poly)phenols and the Gut-Brain Axis in Ageing

• Does Nutritional Supplementation Have a Disease-Modifying Effect on the Alzheimer's Disease Neurodegenerative Process?

• Eating frequency, timing and duration in relation to cognitive performance and AD biomarkers in adults

• Effects of dietary supplements, foods, and dietary patterns in Parkinson's disease: meta-analysis and systematic review of randomized and crossover studies

• Effect of time-restricted eating and intermittent fasting on cognitive function and mental health in older adults: A systematic review

• Effects of virgin coconut oil consumption on serum brain-derived neurotrophic factor levels and oxidative stress biomarkers in adults with metabolic syndrome: a randomized clinical trial

• Efficacy and safety of Ferrous iron on the prevention of Vascular cOgnitive impaiRment among patients with cerebral Infarction/TIA (FAVORITE): rationale and design of a multicentre randomised trial

• Eicosapentaenoic acid activates the P62/KEAP1/NRF2 pathway for the prevention of diabetes-associated cognitive dysfunction

• Functional outcomes of diets in multiple sclerosis (FOOD for MS): Protocol for a parallel arm randomized feeding trial for low glycemic load and calorie restriction

• Gut microbiome, short-chain fatty acids, alpha-synuclein, neuroinflammation, and ROS/RNS: Relevance to Parkinson's disease and therapeutic implications

• Gut microbiota in multiple sclerosis and animal models

• Impact of Serum Vitamin D, B6, and B12 and Cognitive Functions on Quality of Life in Peri- and Postmenopausal Polish Women

• Integrating a multimodal lifestyle intervention with medical food in prodromal Alzheimer's disease: the MIND-AD_mini randomized controlled trial

• Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study

• Lactobacillus rhamnosus GG improves cognitive impairments in mice with sepsis

• Limosilactobacillus reuteri DSM 17938 relieves inflammation, endoplasmic reticulum stress, and autophagy in hippocampus of western diet-fed rats by modulation of systemic inflammation

• Localized Pantothenic Acid (Vitamin B5) Reductions Present Throughout the Dementia with Lewy Bodies Brain

• Long-term calorie restriction reduces oxidative DNA damage to oligodendroglia and promotes homeostatic microglia in the aging monkey brain

• MAO inhibiting phytochemicals from the roots of Glycyrrhiza glabra L

• Molecular Dynamics Simulation Study of the Self-Assembly of Tau-Derived PHF6 and Its Inhibition by Oleuropein Aglycone from Extra Virgin Olive Oil

• Multidomain Dementia Risk Reduction in Primary Care is Feasible: A Proof-of-concept study

• Natural Antioxidants: An Effective Strategy for the Treatment of Alzheimer's Disease at the Early Stage

• Nobiletin regulates intracellular Ca²⁺ levels via IP₃R and ameliorates neuroinflammation in Aβ42-induced astrocytes

• Olive oil tyrosols reduce α-synuclein aggregation in vitro and in vivo after ingestion in a Caenorhabditis elegans Parkinson's model

• Oral Administration of Bifidobacterium lactis Ameliorates Cognitive Deficits in Mice Intracerebroventricularly Administered Amyloid Beta via Regulation the Activation of Mitogen-activated Protein Kinases

• Physicochemistry, Nutritional, and Therapeutic Potential of Ficus carica - A Promising Nutraceutical

• Prevalence and patterns of vitamin D deficiency and its role in cognitive functioning in a cohort from South India

• Saffron (Crocus sativus L.) extract attenuates chronic scopolamine-induced cognitive impairment, amyloid beta, and neurofibrillary tangles accumulation in rats

• Short-chain fatty acids: Important components of the gut-brain axis against AD

• The association between adherence to the EAT-Lancet diet and cognitive ageing

• The association of ultra-processed food intake with neurodegenerative disorders: a systematic review and dose-response meta-analysis of large-scale cohorts

• The associations between nutritional status and physical frailty and Alzheimer's disease plasma biomarkers in older cognitively unimpaired adults with positive of amyloid-β PET

• The Gut Microbiota in Parkinson Disease: Interactions with Drugs and Potential for Therapeutic Applications

• The Mediterranean diet is not associated with neuroimaging or cognition in middle-aged adults: a cross-sectional analysis of the PREVENT dementia programme

• The shift in the fatty acid composition of the circulating lipidome in Alzheimer's disease

• Vitamin D, Cognition, and Alzheimer's Disease: Observational and Two-Sample Mendelian Randomization Studies

Mood and Mental Health

• A randomized controlled trial to compare the effects of time-restricted eating versus Mediterranean diet on symptoms and quality of life in bipolar disorder

• Adherence to unhealthy diets is associated with altered frontal gamma-aminobutyric acid and glutamate concentrations and grey matter volume: preliminary findings

• Association between different triglyceride glucose index-related indicators and depression in premenopausal and postmenopausal women: NHANES, 2013-2016

• Association between serum 25-hydroxyvitamin D3 level and cognitive impairment in older chronic kidney disease patients

• Association between thiamine intake and depression: A national cross-sectional study

• Associations between fruit and vegetable intakes and incident depression in middle-aged and older adults from 10 diverse international longitudinal cohorts

• Associations Between Vitamin K and Suicide Attempts in Patients with Depression: A Case-Control Study

• Association of serum 25-hydroxyvitamin d concentrations with all-cause and cause-specific mortality among individuals with depression: A cohort study

• A reply to the commentary on 'The association between gut-health promoting diet and depression: A mediation analysis'

• Comparison of the Protective Effects of Casein Hydrolysate Containing Tyr-Pro-Val-Glu-Pro-Phe and Casein on the Behaviors and Peripheral and Brain Functions in Mice with Chronic-Stress-Induced Anxiety and Insomnia

• Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis of Epidemiologic Studies

• Effect of gut microbiome on serotonin metabolism: a personalized treatment approach

• Factors associated with depressive symptoms among cancer patients: a nationwide cross-sectional study

• Fish consumption and depression in Korean population: The Korea National Health and Nutrition Examination Survey, 2013-2021

• Gut microbiota composition links to variation in functional domains across psychiatric disorders

• Intake of dietary advanced glycation end products may be associated with depression and sleep quality in young adults

• Latent profile analysis of vitamin D and its association with depression severity of hospitalized patients with bipolar depression

• Low-carbohydrate-diet score, dietary macronutrient intake, and depression among adults in the United States

• Maternal pre-pregnancy diet and prenatal depression: The mediating role of pre-pregnancy weight status and prenatal inflammation

• Mediterranean Diet and Mental Health in Children and Adolescents: A Systematic Review

• Milk fat globule membranes for psychological and physical health: qualitative results from the Employing Milk Phospholipids to Observe Well-being and Emotional Resilience (EMPOWER) randomised trial

• PROVIT-CLOCK: A Potential Influence of Probiotics and Vitamin B7 Add-On Treatment and Metabolites on Clock Gene Expression in Major Depression

• Raspberry Ketone Prevents LPS-Induced Depression-Like Behaviors in Mice by Inhibiting TLR-4/NF-κB Signaling Pathway via the Gut-Brain Axis

• Sex-specific effects of ketogenic diet on anxiety-like behavior and neuroimmune response in C57Bl/6J mice

• The associations between plant-based dietary indices with depression and quality of life and insomnia among Iranian adolescent girls in 2015

• The impact of high-fat diet consumption and inulin fiber supplementation on anxiety-related behaviors and liver oxidative status in female Wistar rats

• The impact of nutrition on psycho-affective status in an older Cretan population: a cross-sectional study

• The potential beneficial effects of Lactobacillus plantarum GM11 on rats with chronic unpredictable mild stress- induced depression

• Time restricted eating and depression: a psychological perspective

• Vitamin B12 overdose may trigger the onset of mixed-state bipolar disorder: A case report

Eating Disorders

• Association of body mass index with progression from binge-eating behavior into binge-eating disorder among adolescents in the United States: A prospective analysis of pooled data

• Associations between dieting practices and eating disorder attitudes and behaviors: Results from the Canadian study of adolescent health behaviors

• Bioelectrical Impedance Vector Analysis, Nutritional Ultrasound^®, and Handgrip Strength as Innovative Methods for Monitoring Critical Anorexia Nervosa Physical Recovery: A Pilot Study

• Cognitive-behavioral therapy for avoidant/restrictive food intake disorder: A proof-of-concept for mechanisms of change and target engagement

• Dietary intake of adults with eating disorders: A systematic review and meta-analysis

• Dismantling the myth of "all foods fit" in eating disorder treatment

• Energy expenditure during nutritional rehabilitation: a scoping review to investigate hypermetabolism in individuals with anorexia nervosa

• Fatty Acids and Their Lipogenic Enzymes in Anorexia Nervosa Clinical Subtypes

• Identifying factors that predict the onset and persistence of fasting for weight control: Prospective findings

• Inpatient treatments for adults with anorexia nervosa: a systematic review of literature

• On the prevalence of 'food addiction' in persons with bulimia nervosa

• Relationships among Alexithymia, Psychological Distress, and Disordered Eating Behaviors in Adolescents

• Rule-based systems to automatically count bites from meal videos

• Sex differences in electrolyte abnormalities indicating refeeding syndrome risk among hospitalized adolescents and young adults with eating disorders

• Sustained insulin treatment restoring metabolic status, body weight, and cognition in an anorexia nervosa-like animal model in mice

• The emerging role of glucagon-like peptide 1 in binge eating

• The natural course of binge-eating disorder: findings from a prospective, community-based study of adults

• The relationship between food selectivity and stature in pediatric patients with avoidant-restrictive food intake disorder - an electronic medical record review

• Variation in care for inpatients with avoidant restrictive food intake disorder leads to development of a novel inpatient clinical pathway to standardize care

Addiction, Eating Behavior and Food Choice

• A Complex Interplay Between Nutrition and Alcohol Use Disorder: Implications for Breaking the Vicious Cycle

• Amylin Modulates a Ventral Tegmental Area-to-Medial Prefrontal Cortex Circuit to Suppress Food Intake and Impulsive Food-Directed Behavior

• Appetite, food intake, and gut hormone responses to glycomacropeptide protein ingestion in older adults: A feasibility, acceptability, and pilot study

• Association between nutrition self-efficacy, health locus of control and food choice motives in consumers in nine European countries

• Circadian influences on feeding behavior

• Construct validity and reliability of a French-Canadian translation of the eating in the absence of hunger questionnaire for children and adolescents

• Current perspectives on brain circuits involved in food addiction-like behaviors

• Depression and emotional eating in children and adolescents: A systematic review and meta-analysis

• Eating preferences and behaviors of older immigrants in Oslo: A qualitative study

• Excessive sucrose consumption reduces synaptic density and increases cannabinoid receptors in Göttingen minipigs

• FGF21 as a mediator of adaptive changes in food intake and macronutrient preference in response to protein restriction

• Folic Acid Ameliorates Anxiety- and Depressive-Like Behavior Induced by Nicotine Withdrawal Through Restoration of Behavioral and Biochemical Alterations in Adolescent Male Rats

• From Pixels to Palate: Communication Around #vegan on Instagram and Its Relation With Eating Intentions

• Functional alterations in overweight/obesity: focusing on the reward and executive control network

• "I find it hard to change poor food habits": Measuring food choice motives in an emerging economy

• Impact of SMAASH-C, a novel nutritional supplement, on drug-seeking and toxicity in female and male rats

• Improving dietary patterns in obese mice: Effects on body weight, adiposity, anhedonia-like behavior, pro-BDNF expression and 5-HT system

• Independent effects of volume and energy density manipulation on energy intake and appetite in healthy adults: A randomized, controlled, crossover study

• Inhibitory control mediates the effect of high intensity interval exercise on food choice

• Operant Training for Highly Palatable Food Alters Translating Messenger RNA in Nucleus Accumbens D₂ Neurons and Reveals a Modulatory Role of Ncdn

• Potential of the Blue Calm® food supplement in the treatment of alcohol withdrawal-induced anxiety in adult zebrafish (Danio rerio)

• The impact of the COVID-19 pandemic on dietary behaviors among school-age children, adolescents, and young adults: a systematic review and meta-analysis

• What should I eat today? Evidence, guidelines, dietary patterns and consumer's behavior

Neurodevelopmental Outcomes

• A vegetable fat-based diet delays psychomotor and cognitive development compared with maternal dairy fat intake in infant gray mouse lemurs

• Association between Dietary Patterns during Pregnancy and Children's Neurodevelopment: A Birth Cohort Study

• Association of the retinol to all-trans retinoic acid pathway with autism spectrum disorder

• Central amygdala is related to the reduction of aggressive behavior by monosodium glutamate ingestion during the period of development in an ADHD model rat

• Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1

• Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses

• Evaluating Mineral Biomarkers as Mediators and Moderators of Behavioural Improvements in a Randomized Controlled Trial of Multinutrients for Children with ADHD

• Human-derived fecal microbiota transplantation alleviates social deficits of the BTBR mouse model of autism through a potential mechanism involving vitamin B₆ metabolism

• Human milk, breastfeeding, and early neurodevelopmental outcomes for infants with critical CHD

• Is neurodevelopment impaired in Brazilian children with intestinal failure on prolonged parenteral nutrition? A single center study

• Lutein supplementation for early-life health and development: current knowledge, challenges, and implications

• Maternal Fiber Intake During Pregnancy and Development of Attention-Deficit/Hyperactivity Disorder Symptoms Across Childhood: The Norwegian Mother, Father, and Child Cohort Study

• Micronutrients for ADHD in youth (MADDY) study: comparison of results from RCT and open label extension

• Nurturing development: how a mother's nutrition shapes offspring's brain through the gut

• Precision synbiotics increase gut microbiome diversity and improve gastrointestinal symptoms in a pilot open-label study for autism spectrum disorder

• Short-term effects of an elimination diet and healthy diet in children with attention-deficit/hyperactivity disorder: a randomized-controlled trial

• The symptomatology of Attention-Deficit/Hyperactivity Disorder and the genetic control of vitamin D levels

• Theobromine improves hyperactivity, inattention, and working memory via modulation of dopaminergic neural function in the frontal cortex of spontaneously hypertensive rats

Sleep Health and Insomnia

• Association between circulating antioxidants and sleep disorders: comprehensive results from NHANES 2017-2018

• Dietary inflammatory index (DII) and sleep quality, duration, and timing: A systematic review

• Dietary Supplementation with an Extract of Aloysia citrodora (Lemon verbena) Improves Sleep Quality in Healthy Subjects: A Randomized Double-Blind Controlled Study

• Improvement of sleep duration and quality through GABA_A receptor by whey protein hydrolysate containing DIQK as the active main compound

Brain Injury

• Omega-3 fatty acid diglyceride emulsions as a novel injectable acute therapeutic in neonatal hypoxic-ischemic brain injury

• Rosmarinic acid ameliorated oxidative stress, neuronal injuries, and mitochondrial dysfunctions mediated by polyglutamine and ɑ-synuclein in Caenorhabditis elegans models

Migraines, Epilepsy and Other Neurological

• α-linolenic acid ameliorates pentylenetetrazol-induced neuron apoptosis and neurological impairment in mice with seizures via down-regulating JAK2/STAT3 pathway

• Age and sex differences in the association between Dietary Inflammatory Index and severe headache or migraine: a nationwide cross-sectional study

• Alzheimer's disease and epilepsy: Research hotspots for comorbidity in the era of global aging

• Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes

• A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epilepsy

• Case Report: Initial Successful Treatment of Migraine and Irritable Bowel Syndrome With a Low-FODMAP Diet

• Effects of a Ketogenic Diet on the Assessment of Biochemical and Clinical Parameters in Duchenne Muscular Dystrophy: A Preclinical Investigation

• Literature Review: Support for caregivers of children on the ketogenic diet for epilepsy and other neurologic disorders

• New horizons for the study of saffron (Crocus sativus L.) and its active ingredients in the management of neurological and psychiatric disorders: A systematic review of clinical evidence and mechanisms

• Short-chain fatty acids: bridges between diet, gut microbiota, and health

• The association between carbohydrate quality index and headache severity, disability and duration among women with migraine : a cross-sectional study

• Typical and atypical MRI abnormalities in Wernicke's encephalopathy: Correlation with blood vitamin B1 levels

• Urine 5-Hydroxyindoleacetic Acid Negatively Correlates with Migraine Occurrence and Characteristics in the Interictal Phase of Episodic Migraine

• Vitamin D and tension-type headache: causal association or epiphenomenon?

• Volume-based enteral feeding for ward patients with acute neurological conditions: a pilot prospective cohort study

• Weight and Muscle Mass Loss Associated with Acute Disease Can be Reversed with Appropriate Nutrition Therapy and Exercise in a Patient with Amyotrophic Lateral Sclerosisa: A Case Report

Other

• High-Caloric Diets in Adolescence Impair Specific GABAergic Subpopulations, Neurogenesis, and Alter Astrocyte Morphology

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Copyright © 2024 Sarah Thomsen Ferreira.