Brain Food Digest for June 16-30, 2024

What's New in Nutrition and Brain Health

Today's research summary includes insights into validated tests to assess the impact of nutritional supplementation on cognitive health outcomes, potential for the polyphenol punicalagin (in pomegranate) to address mild cognitive impairment, sequential treatment with MAD and LGIT dietary therapies for drug-resistant pediatric epilepsy, and much more.

Key: *Full text available **Section summaries available

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Sarah Ferreira, MS, MPH, RD

Research Area

• Cognitive Function, Memory and Neurodegeneration

• Mood and Mental Health

• Eating Disorders

• Addiction, Eating Behavior and Food Choice

• Neurodevelopmental Outcomes

• Brain Injury

• Migraines, Epilepsy and Other Neurological

• Other

Cognitive Function, Memory and Neurodegeneration

Adherence to the planetary health diet and cognitive decline: findings from the ELSA-Brasil study

*Alignment of Consumers’ Expected Brain Benefits from Food and Supplements with Measurable Cognitive Performance Tests

**Brain responses to intermittent fasting and the healthy living diet in older adults

*Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease

**Combating Parkinson's Disease with Plant-Derived Polyphenols: Targeting Oxidative Stress and Neuroinflammation

*Combined Effect of Red Wine and Mocha Pot Coffee in Mild Vascular Cognitive Impairment

*Dietary factors and risk for amyotrophic lateral sclerosis: A two sample mendelian randomization study

*Effect of olive leaf phytochemicals on the anti-acetylcholinesterase, anti-cyclooxygenase-2 and ferric reducing antioxidant capacity

*Effects of ketogenic diet on cognitive function of patients with Alzheimer's disease: a systematic review and meta-analysis

Effectiveness of dairy products to protect against cognitive decline in later life: a narrative review

*Effectiveness of Flavonoid-Rich Diet in Alleviating Symptoms of Neurodegenerative Diseases

*Flavonoid intake and risk of Parkinson's disease

*Frankincense: A neuronutrient to approach Parkinson's disease treatment

Informal caregiver and healthcare professional perspectives on dementia and nutrition

*Multifactor Analyses of Frontal Cortex Lipids in the APP/PS1 Model of Familial Alzheimer's Disease Reveal Anomalies in Responses to Dietary n-3 PUFA and Estrogenic Treatments

*Natural Health Products for Symptomatic Relief of Parkinson's Disease: Prevalence, Interest, and Awareness

Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin

**Neuroprotective effects of chlorogenic acid: Modulation of Akt/Erk1/2 signaling to prevent neuronal apoptosis in Parkinson's disease

Neuroprotective effects of flavonoids: endoplasmic reticulum as the target

**Nicotinamide Riboside Ameliorates Survival Time and Motor Dysfunction in an MPTP-Induced Parkinson's Disease Zebrafish Model through Effects on Glucose Metabolism and Endoplasmic Reticulum Stress

**Pomegranate polyphenol punicalagin as a nutraceutical for mitigating mild cognitive impairment: An overview of beneficial properties

*Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease

Relationship of Curcumin with Aging and Alzheimer and Parkinson Disease, the Most Prevalent Age-Related Neurodegenerative Diseases: A Narrative Review

*Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine

*The effects of omega-3, DHA, EPA, Souvenaid® in Alzheimer's disease: A systematic review and meta-analysis

The impact of malnutrition on cognition in older adults: A systematic review

*The impact of six-week dihydrogen-pyrroloquinoline quinone supplementation on mitochondrial biomarkers, brain metabolism, and cognition in elderly individuals with mild cognitive impairment: a randomized controlled trial

The Role of Cobalamin in Multiple Sclerosis: An Update

Tongue pressure is a strong predictor of recommendation for gastrostomy in amyotrophic lateral sclerosis

Mood and Mental Health

Assessment of the relation between depression, frailty, nutrition and quality of life among older adults: findings from a cross-sectional study in Greece

*Association between vitamin D insufficiency and depressive symptoms, and functional disability in community-dwelling Brazilian older adults: results from ELSI-Brazil study

Associations of nutrition impact symptoms with depression in patients with advanced cancer

*Cross-sectional study examining the association between diet quality and the prevalence of anxiety and depression in UK undergraduate students

**Effect of Low-Fat Diet on Depression Score in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

*Effectiveness of Vitamin D on Neurological and Mental Disorders

*Efficacy and safety of omega-3 fatty acids supplementation for anxiety symptoms: a systematic review and dose-response meta-analysis of randomized controlled trials

*Sleep, Mood, and Nutrition Patterns of Postmenopausal Women Diagnosed with Major Depressive Disorder by Menopause Periods

*The Role of Water-Soluble Vitamins and Vitamin D in Prevention and Treatment of Depression and Seasonal Affective Disorder in Adults

Treating chronic stress and chronic pain by manipulating gut microbiota with diet: can we kill two birds with one stone?

*Vitamin D supplementation during pregnancy and the role of maternal prenatal depression

Eating Disorders

*A prospective observational study comparing rates of medical instability between adolescents with typical and atypical anorexia nervosa

*Food addiction and the physical and mental health status of adults with overweight and obesity

*Health behavior and psychological treatment utilization in adults with avoidant/restrictive food intake disorder symptoms

*Is Adherence to the Saudi Healthy Plate Dietary Guidelines Associated with Eating Concerns Symptoms among Saudi Young Females?

*The experiences of a therapeutic relationship between dietitians and patients in UK eating disorder treatment: A qualitative study

*Ultra-Processed Foods and Mental Health: Where Do Eating Disorders Fit into the Puzzle?

Addiction, Eating Behavior and Food Choice

*Correction: A novel weight suppression score associates with distinct eating disorder and ultra-processed food addiction symptoms compared to the traditional weight suppression measure among adults seeking outpatient nutrition counseling

Dietary supplementation with a wild green oat extract (Avena sativa L.) to improve wellness and wellbeing during smoking reduction or cessation: a randomized double-blind controlled study

*Gut microbiota signatures of vulnerability to food addiction in mice and humans

Neurodevelopmental Outcomes

Medical Comorbidities, Nutritional Markers, and Cardiovascular Risk Markers in Youth With ARFID

Newborn Dried Blood Spot Folate in Relation to Maternal Self-reported Folic Acid Intake, Autism Spectrum Disorder, and Developmental Delay

*Prenatal air pollution and children's autism traits score: Examination of joint associations with maternal intake of vitamin D, methyl donors, and polyunsaturated fatty acids using mixture methods

Prenatal vitamin D levels and infant cognitive, motor, language and social-emotional development at 6 and 9 months of age

Relationship between vitamin B12 levels and motor development: A systematic review

**Sex-dependent susceptibility to brain metabolic dysfunction and memory impairment in response to pre- and postnatal high-fat diet

The prevalence of neural tube defects and their prevention by folic acid supplementation

Brain Injury

*Nutritional interventions and related efforts addressing undernutrition during rehabilitation after acquired brain injury: a scoping review protocol

Migraines, Epilepsy and Other Neurological

Advances in Ketogenic Diet Therapies in Pediatric Epilepsy: A Systematic Review

Association of dietary vitamin C consumption with severe headache or migraine among adults: a cross-sectional study of NHANES 1999-2004

*Effects of Enteral Nutrition Support with Ultrasound-guided Three-lumen Gastrojejunal Tube Insertion on Success Rate of Catheterization, Nutritional Status and Aspiration Rate in Patients with Severe Neurological Diseases

Executive function impairment is associated with low serum vitamin D levels in children with epilepsy

Inflammation and oxidative stress in epileptic children: from molecular mechanisms to clinical application of ketogenic diet

Intermittent and periodic fasting - Evidence and perspectives in multiple sclerosis

Ketogenic Diets Alter the Gut Microbiome, Resulting in Decreased Susceptibility to and Cognitive Impairment in Rats with Pilocarpine-Induced Status Epilepticus

*Mediterranean ketogenic diet accounts for reduced pain frequency and intensity in patients with chronic migraine: A pilot study

Potential causal association of diabetes mellitus and blood glucose related indexes with the onset of epilepsy: a two-sample Mendelian randomization study

*Sequential Treatment with Modified Atkins Diet and Low Glycemic Index Treatment for Drug-Resistant Epilepsy in Children

Other

Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency

Volumetric brain reductions in adult patients with phenylketonuria and their relationship with blood phenylalanine levels

Disclaimer: The information provided in this newsletter is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in this newsletter. Reliance on any information provided in this newsletter is solely at your own risk. The authors and publishers of this newsletter are not liable for any losses, injuries, or damages arising from the use of the information provided.

Copyright © 2024 Sarah Thomsen Ferreira.